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the main functioning component of zyban gsk is a chemical compound called bupropion hydrochloride.

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the results of our placebo-controlled study support previous preliminary data that bupropion sr, at a dosage of 150 to 300 mg day, may be clinically effective for the treatment of neuropathic pain, according to study author marilyn semenchuk, pharmd, of the department of neurology at the university of arizona at tucson.

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coadministration may cause serotonin syndrome do not use concomitantly or initiate bupropion within 14 days of stopping an maoi conversely, at least 14 days should be allowed after stopping bupropion before starting an maoi antidepressant starting bupropion in a patient who is being treated with linezolid or iv methylene blue is contraindicated because of an increased risk of serotonin syndrome if linezolid or iv methylene blue must be administered, discontinue bupropion immediately and monitor for cns toxicity; may resume 24 hr after last linezolid or methylene blue dose or after 2 weeks of monitoring, whichever comes first.

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bupropion, cyclobenzaprine, dextromethorphan, a maoi eg, phenelzine , meperidine, methadone, a norepinephrine reuptake inhibitor eg, atomoxetine , oral selegiline, propoxyphene, a serotonin or norepinephrine reuptake inhibitor eg, duloxetine, venlafaxine , sibutramine, a ssri eg, fluoxetine , st.

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